[Abstract]: Based on a comprehensive review and critical analysis of the literature regarding the effects of sodium bicarbonate supplementation on exercise performance, conducted by experts in the field and selected members of the International Society of Spor
Sodium Bicarbonate
Exercise performance and recovery is the main area connected here, and any felt benefit should be read together with the human evidence base.
Some human supplement-context evidence is present and directly informs the score.
Representative tier calculated from paper evidence that passed the collection audit.
Main benefit evidence
The representative ingredient tier is calculated from these target-level evidence groups.
Exercise performance and recovery7 studiesTier-AExercise performance and recoveryFairly consistent positive signal in studiesFelt benefit focusSupplement contextPotential benefit studied in Exercise performance and recovery.Open metrics>
Recent research
10 new papers were added in this period. No new risk signal was identified.
What's new
Most notable recent finding
Study dosage range (reference only)
Key cautions to review
Standalone side-effect signals and combination cautions are listed separately.
Standalone side effects
Better-than-solo signal
Shown only when a combination group did better than single use in a study. Not a recommendation to combine.
Evidence summaries
Paper IDs and full lists are private. Only study types and summaries are shown.
NaBicarb therapy in patients with CKD stages 3 and 4 significantly increases serum bicarbonate and decreases potassium levels and there were no significant differences in eGFR, BP, weight, serious adverse events or the levels of muscle gene expression between
Mechanical links between skeletal muscle fatigue, proton accumulation (or metabolic acidosis) and NaHCO3 supplementation have been identified to provide a more targeted, evidence-based approach to direct future research, as well as provide practitioners with a
3 more summariesLimited representative sample by study type.>
It is suggested that NaHCO3 supplementation could prevent the decline in skilled tennis performance after a simulated match.
The mechanism for improved exercise with SB was consistently in place prior to exercise, although this only resulted in a likely improvement in one trial, and results suggest that caution should be taken when interpreting the results from single trials as to t
CAP can mitigate GI symptoms induced with SOL and should be ingested earlier to induce similar acid-base changes, and may be more ergogenic in those who experience severe GI distress with SOL, although this warrants further investigation.