biotech

Bio-Analyst

Research Platform
person
Tier-BPublic-ready6/20/2026

Saffron

Stress Response and Sleep Changes is the main area connected here, and any felt benefit should be read together with the human evidence base.

Some human supplement-context evidence is present and directly informs the score.

Representative tier calculated from paper evidence that passed the collection audit.

Papers analyzed
49
Caution signal
Low
Representative score
66.8
Stress Response and Sleep Changes

Main benefit evidence

The representative ingredient tier is calculated from these target-level evidence groups.

Stress and mood
1 studiesTier-C
Stress Response and Sleep Changes
Some positive signal observedFelt benefit focusSupplement context
These findings come from stress response, cortisol, anxiety, or sleep outcomes. They may mix felt benefits with physiological markers.
Open metrics
>
Stress and mood balance
No direct rate reported. Read direction and evidence strength together.
Evidence score
40.9
Score reflects signal strength. Tier also considers paper count, repetition, and study context.

Recent research

Updated This Month10 new papers

10 new papers were added in this period. No new risk signal was identified.

What's new

10 new papers were added.No new risk signal was identified.

Most notable recent finding

This is the most meaningful new study in the latest update.
review
Why it mattersIt ranked highest among the newly collected papers for this ingredient in the latest update.
View paper

Study dosage range (reference only)

Lower dose
30
mg/day
Higher dose
30
mg/day
Dosages used in research papers, shown as reference context.
Not personal dosing instructions, recommendations, or safety limits.

Key cautions to review

Standalone side-effect signals and combination cautions are listed separately.

Caution index
0.6
Caution band: Low
Caution signals
0
Side effects + combos + curated rules
Key precautions
No combination caution signal is clear enough to show right now. This does not guarantee safety.
Standalone side effects, combination cautions, and positive combos are separated below.

Side-effect and combination signals

No standalone side-effect or combination signal is currently clear enough to show from the collected papers. This does not mean there is no concern.

Evidence summaries

Paper IDs and full lists are private. Only study types and summaries are shown.

Key Evidence #1
Public scholarly dataCitation signal: 224
review

An overview of the historical, economic, genetic, botanical, agronomic and qualitative traits of saffron as well as the properties, traditional and recent uses of the spice as wellAs its by-products such as tepals, stamens, styles, corms and leaves.

Key Evidence #2
Public scholarly dataCitation signal: 199
review

The objective of this work was to provide an updated and critical review of the research on the therapeutic properties of saffron, including activity on the nervous and cardiovascular systems, in the liver, its antidepressant, anxiolytic and antineoplastic pro

Key Evidence #3
Public scholarly dataCitation signal: 149
review

Saffron, the dried stigma of the Crocus sativus flower, is considered among the main terroir products of Morocco and a spice incorporated in many dishes around the world.

3 more summariesLimited representative sample by study type.
>
Public scholarly dataCitation signal: 110
observational

This plant and its active compounds could be a beneficial medicinal food ingredient in the formation of drugs targeting nervous system disorders, and multiple preclinical and clinical studies have supported neuroprotective, anxiolytic, antidepressant, learning

Public scholarly dataCitation signal: 106
observational

The effect of crocin as a potent antioxidant and neuroprotective for treatment of refractory DME in the short term is indicated, however, the clinical significance is yet to be proved in a study with larger sample size and longer duration of follow-up and also

Public scholarly dataCitation signal: 103
review

The phytochemical profile of saffron confers many beneficial virtues on human health and, in particular, on the prevention of age-related diseases, which is a major asset reinforcing the interest for this medicinal plant.

Saffron
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