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arrow_backExplore/Lion's Mane
Public-ready7/6/2026

Lion's Mane

Papers analyzed
90
Cognition, memory, and focusExercise performance and recoveryImmune and respiratory support

Main benefit evidence

Review human evidence by goal.

Cognition and focus
Cognition, memory, and focus
Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Exercise performance and recovery
Exercise performance and recovery
Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Immune and respiratory health
Immune and respiratory support
Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Stress and mood
Stress Response and Sleep Changes
Goal tierNot rated yet

No direct evidence for general supplement use is confirmed under the current standard.

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Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution signals
2
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Stomach discomfort, headache, and allergic reactions1 papers
The review notes potential side effects of Hericium erinaceus include stomach discomfort, headache, and allergic reactions, though these are commonly unreported.Human studies · Systematic review
gastrointestinal disturbance1 papers
Clinical studies indicate that Hericium erinaceus is generally well tolerated, with gastrointestinal disturbance identified as the most common adverse effect.Human studies · Systematic review