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Public-ready6/30/2026

Iron

Papers analyzed
50
Blood-Level or Deficiency MarkerBlood pressure and vascular health markersMenstrual and women's health
What to look for in this research

Blood-Level or Deficiency Marker is closer to a research marker, so it should be read separately from a directly felt benefit.

Main benefit evidence

Review human evidence by goal.

Nutrient status and deficiency
Blood-Level or Deficiency Marker
Measured outcomes: Blood level or deficiency correction markers

This is based on lab markers such as blood levels, deficiency correction, or absorption. Read it separately from directly felt outcomes.

Goal tierNot rated yet

No direct evidence for general supplement use is confirmed under the current standard.

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Blood pressure and vascular health
Blood pressure and vascular health markers
Measured outcomes: Blood pressure and vascular markers

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Women's health
Menstrual and women's health
Measured outcomes: Menstrual and women's health

Potential benefit studied in Women's health. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Immune and respiratory health
Immune and respiratory support
Measured outcomes: Immune and respiratory support

Potential benefit studied in Immune and respiratory health. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Blood lipids
Cholesterol and triglycerides
Measured outcomes: Cholesterol and triglycerides

Potential benefit studied in Blood lipids. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Glucose and metabolic health
Glucose and metabolic health markers
Measured outcomes: Glucose and metabolic markers

This card is closer to a measured biomarker or lab outcome than a directly felt user benefit. These findings come from a defined study population, so everyday effects may differ.

Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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What does a research result actually tell you?

Reading research

Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution signals
5
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Side effects1 papers
Women receiving intermittent iron supplements were less likely to experience adverse side effects compared to those receiving daily supplements, though side effects were still more common than in the control group.Human studies · Systematic review
Nausea1 papers
Daily oral iron supplementation significantly increased odds of nausea (adjusted OR 3.56, p<0.001) compared to intermittent supplementation in pregnant women.Human studies · Meta-analysis
Diarrhea1 papers
Daily oral iron supplementation significantly increased odds of diarrhea (adjusted OR 5.40, p=0.002) compared to intermittent supplementation in pregnant women.Human studies · Meta-analysis
Constipation1 papers
Daily oral iron supplementation significantly increased odds of constipation (adjusted OR 1.95, p=0.006) compared to intermittent supplementation in pregnant women.Human studies · Meta-analysis
Incidence of diarrhea1 papers
Both SQ-LNS products increased the incidence and longitudinal prevalence of diarrhea, vomiting, and rash/sores.Human studies · Randomized controlled trial