Exercise performance and recovery is the main area connected here, and any felt benefit should be read together with the human evidence base.
Some human supplement-context evidence is present and directly informs the score.
Representative tier calculated from paper evidence that passed the collection audit.
The representative ingredient tier is calculated from these target-level evidence groups.
10 new papers were added in this period. No new risk signal was identified.
Standalone side-effect signals and combination cautions are listed separately.
Paper IDs and full lists are private. Only study types and summaries are shown.
The evidence generally supports that consumption of up to 400 mg caffeine/day in healthy adults is not associated with overt, adverse cardiovascular effects, behavioral effects, reproductive and developmental effects, acute effects, or bone status and a shift
It is suggested that caffeine ingestion improves exercise performance in a broad range of exercise tasks and the magnitude of the effect of caffeine is generally greater for aerobic as compared with anaerobic exercise.
A single and moderate dose of caffeine, ingested 5–60 min before a soccer practice, might produce valuable improvements in certain abilities related to enhanced soccer physical performance, however, caffeine does not seem to cause increased markers of muscle d
Low-doses of E GCG and caffeine used in combination led to synergistic anti-obesity effects equivalent to those of high-dose EGCG, and combination treatment exhibited a synergistic effect on altering gut microbiota, including decreased Firmicutes level and inc
It is shown that eicosanoyl-5-hydroxytryptamide, which was purified from coffee as an agent that leads to enhanced enzymatic activity of the specific phosphatase PP2A that dephosphorylates the pathogenic protein α-synuclein, works in synergy with caffeine in p
[Abstract]: Caffeine used as a supplement has been shown to improve physical and cognitive performance in several sport modalities due to its effects on the central nervous system. This review assesses the direct effects of caffeine supplementation on performa